Enzymes and Inhibitors
Gold Biotechnology Inc D Luciferin Potassium Salt 4g
L uciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2 as cofactors to emit a characteristic yellow-green emission in the presence of oxygen which shifts to red light in vivo at 37 C Through the utilization of ATP the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain
Medchemexpress LLC NQO1 substrate | 50MG
NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC[1]
Medchemexpress LLC 6'-Amino-D-luciferin | 161055-47-6 | 98.5% | 25 MG
6'-Amino-D-luciferin is a derivative of D-luciferin with an amino group replacing the 6-hydroxyl group. It serves as a natural substrate of luciferase (Luc) and is utilized for IVIS imaging in various cell and animal experimental settings.
- Derivative of D-luciferin
- Features an amino group replacing the 6-hydroxyl group
- Natural substrate for luciferase (Luc)
- Applicable for IVIS imaging in cell and animal experiments
- Red-shifts bioluminescence spectrum of green-yellow emitting luciferase
- Blue-shifts bioluminescence spectrum of red-emitting luciferase
- Used to analyze interaction of binding mutant active sites (λmax=588 nm)
- Capable of detecting apoptotic signals in tumor models
CPC Scientific H-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg-OH (trifluoroacetate salt) 1MG
SEQUENCE: H-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: KRREILSRRPSYRMOLECULAR FORMULA: C73H129N29O19MOLECULAR WEIGHT: 1716.99STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [149155-45-3]SYNONYMS: RESEARCH AREA: ApoptosisREFERENCES:
Colbran, Janet L., et al. Biochemistry and Cell Biology 70.10-11 (1992): 1277-1282.SKU(s): SUBS-013A, SUBS-013B
Medchemexpress LLC Boc-Gln-Ala-Arg-AMC (acetate) | 00-00-0 | 99.7% | 690.74 g/mol | C31H46N8O10 | 5 MG
Boc-Gln-Ala-Arg-AMC acetate is an AMC-labeled peptide substrate for fluorescence-based protease assays. Enzymatic cleavage liberates the AMC fluorophore, producing a measurable fluorescent signal used in activity assays and screening applications.
- Fluorogenic peptide substrate for protease activity assays.
- Releases fluorescent AMC upon enzymatic hydrolysis.
- Validated for trypsin and TMPRSS2 activity measurement.
- High purity (99.7%) by HPLC.
- Available in small pack sizes suitable for assay development.
Medchemexpress LLC HER2/CD340 Human B 100ug | 100ug
The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics Upon activation it triggers the MEMO1-RHOA-DIAPH1 pathway inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization HER2/CD340 Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived HER2/CD340 protein expressed by HEK293 with C-Avi C-His labeled tag
Apexbio Technology LLC D-Luciferin(Synonyms: Firefly Luciferin, Luciferin, Beetle Luciferin, (S)-2-(6'-Hydroxybenzothiazolyl)-Δ2-thiazoline-4-carboxylic acid), 5mg, CAS: 2591-17-5.
D-Luciferin (CAS 2591-17-5) is a membrane-permeable bioluminescent substrate for firefly luciferase characterized by a Km of approximately 2 M In the presence of ATP luciferin undergoes oxidation and decarboxylation catalyzed by luciferase emitting measurable photons This bioluminescence enables quantification of intracellular ATP levels both in vitro and in vivo In biomedical research D-Luciferin is commonly applied for monitoring promoter-driven luciferase gene expression and as a non-invasive imaging probe in bioluminescence imaging (BLI) studies to assess tumor burden pharmacodynamics and cellular ATP content
Medchemexpress LLC D-Luciferin 6 -methy 10mg | 24404-90-8 | 294.35 g/mol | C12H10N2O3S2 | 10 MG
D-luciferin 6′-methyl ether is a D-luciferin analogue that acts as a potent inhibitor of Photinus pyralis luciferase (PpyLuc). It is provided as a solid reagent for biochemical and cell-based assays to probe luciferase activity and inhibitor interactions. Typical reported purity is ~99.5% and the molecular weight is 294.35 g/mol.
- Potent PpyLuc inhibitor with reported IC50 around 0.1 μM.
- Suitable for biochemical and cell-based assay applications.
- High reported purity for reliable experimental results.
- Stable when stored protected from light at 4°C; in solvent store at -80°C for long term.
- For research use only; not for human or clinical use.
Cayman Chemical mP-3 FluorogenIc Substrate 5mg
A fluorogenic substrate for MMP-3; Mca is released upon cleavage by MMP-3 and its fluorescence can be used to quantify MMP-3 activity
STA PHARMACEUTICAL US LLC Fmoc-D-2-Nitrophe | 1 g | CAS 478183-70-9 | MDL MFCD01317714
Fmoc-D-2-Nitrophe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 478183-70-9
- MDL: MFCD01317714
- InChIKey: KVLRWXBYPKSBFY-OAQYLSRUSA-N
- Molecular Weight: 432.432
- Molecular Formula: C24H20N2O6
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-nitrophenyl)propanoic acid
- SMILES: O=C([C@@H](CC1=CC=CC=C1[N+]([O-])=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)O
![eMolecules 115144-35-9 | D-Luciferin potassium salt | Apollo Scientific | MFCD00044928 | 318.410 | C11H7KN2O3S2 | 0.000 | [K+].Oc1ccc2nc(sc2c1)C1=N[C@H](CS1)C([O-])=O | 50mg | 562533489](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000130387.jpg-250.jpg)
eMolecules 115144-35-9 | D-Luciferin potassium salt | Apollo Scientific | MFCD00044928 | 318.410 | C11H7KN2O3S2 | 0.000 | [K+].Oc1ccc2nc(sc2c1)C1=N[C@H](CS1)C([O-])=O | 50mg | 562533489
D-Luciferin potassium salt | Apollo Scientific | 115144-35-9 | MFCD00044928 | 318.410 | C11H7KN2O3S2 | 0.000 | [K+].Oc1ccc2nc(sc2c1)C1=N[C@H](CS1)C([O-])=O | 50mg | 562533489
![eMolecules 115144-35-9 | D-Luciferin potassium salt | Chemodex Ltd. | MFCD00044928 | 318.410 | C11H7KN2O3S2 | 95.000 | [K+].Oc1ccc2nc(sc2c1)C1=N[C@H](CS1)C([O-])=O | 50mg | 482922420](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000128692.jpg-250.jpg)
eMolecules 115144-35-9 | D-Luciferin potassium salt | Chemodex Ltd. | MFCD00044928 | 318.410 | C11H7KN2O3S2 | 95.000 | [K+].Oc1ccc2nc(sc2c1)C1=N[C@H](CS1)C([O-])=O | 50mg | 482922420
D-Luciferin potassium salt | Chemodex Ltd. | 115144-35-9 | MFCD00044928 | 318.410 | C11H7KN2O3S2 | 95.000 | [K+].Oc1ccc2nc(sc2c1)C1=N[C@H](CS1)C([O-])=O | 50mg | 482922420
Medchemexpress LLC Gly-Pro-AMC hydrobromide | 115035-46-6 | 98.68% | 410.26 | 25 MG
Gly-Pro-AMC hydrobromide is a fluorescent dye that serves as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity. It is intended for research use only.
- Fluorescent dye
- Specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity
- Fluorescence detection conditions: excitation wavelength 350 nm, fluorescence emission spectrum detection 450 nm
Avanti Polar Lipids PIP2 POWDER
L- alpha -Phosphatidylinositol-4,5-bisphosphate (Brain, Porcine-Triammonium Salt). 383907-42-4